Determination of related substances of Apomorphine hydrochloride sublingual tablet by HPLC HPLC测定盐酸阿扑吗啡舌下片的有关物质
Conclusions: Medium pain could be relieved by buprenorphine sublingual tablet with less ADRs incidence rate and no intolerance and dependence were observed. 结论:舌下含片丁丙诺啡可有效缓解中度以上疼痛,不良反应发生率较低,且无药物耐受及身体依赖现象。
Study on a Sublingual Tablet of G-0268 G-0268舌下片新剂型的研究
AIM: To evaluate the analgesic effect of initial dose of buprenorphine sublingual tablet in the clinical treatment of cancer pains and the adverse drug reactions ( ADRs). 目的:临床评价初始剂量的丁丙诺啡含片对癌痛的镇痛效果及药物的不良反应。
Objective: To assess the analgesic effects and side effects of buprenorphine sublingual tablet in dental treatment. 目的:临床评价丁丙诺啡舌下含片辅助齿科治疗时的镇痛效果及不良反应。
The results showed that onset for sublingual tablet had a more rapid onset than conventional. The peak concentration of sublingual was higher than conventional tablet. 结果舌下片吸收快、峰浓度高、起效时间明显提前。
Clinical trial of analgesic effects of buprenorphine sublingual tablet in dental treatment 丁丙诺啡对齿科治疗镇痛效果的临床研究
Conclusion: Buprenorphine sublingual tablet can relieve the pain in dental treatment. 结论:丁丙诺啡含片可有效地缓解口腔牙齿治疗时的疼痛,但对抑制开髓治疗时的疼痛效果不明显。
It is suggested that 30~ 40 μ g of DHE sublingual tablet may be used in patients after operation. 观察结果表明,DHE舌下含片顿服30~40μg对手术后患者是适用的。
Thirdly, the stability of G-0268 sublingual tablet was investigated. 建立了G-0268舌下片的稳定性分析方法。
Because of a serious liver first-pass effect, the dosage forms of Naloxone Hydrochloride is mainly used on domestic and aboard clinical practice in the forms of injection and sublingual tablet. 但由于该药肝脏首过效应严重,口服无效,目前国内外临床上供应用的盐酸纳洛酮的剂型为注射液和舌下片。